We show in this paper that mutations in TP53BP1 predict tumor responses to PLX038A, an active metabolite of irinotecan. This is our first collaboration paper…
A new integrated data portal for exploring pediatric cancer genomic data. link is www.pedtranscriptome.org
We show in this paper that glioblastoma lines with EGFR amplification are more sensitive to PARP inhibitor Talazoparib.
Dr. Das was a senior data analyst at the Indian national institute of biomedical genomics before joining us. His project there involved ICGC. He received…
The paper presents evidence that PELP1 is a driver gene in gliomagenesis. Link is here
Siyuan the lab’s current effort on characterizing telomerase and telomeres.
We analyzed the genomic profiles of more than 220 childhood cancer PDX models. Link is here. It is a tremendously useful resource for the pediatric…
This two-year grant will allow her to design new methods to predict drug responses for pediatric cancer using their genetic profiles.