We show in this paper that mutations in TP53BP1 predict tumor responses to PLX038A, an active metabolite of irinotecan. This is our first collaboration paper…

The paper presents evidence that PELP1 is a driver gene in gliomagenesis. Link is here

We analyzed the genomic profiles of more than 220 childhood cancer PDX models. Link is here. It is a tremendously useful resource for the pediatric…

Xiaojing is co-first author on this paper.

This paper shows synonymous mutations in VHL exon 2 may underlie familial pheochromocytoma. We helped mine the TCGA data for VHL splicing patterns. Many thanks…

In collaboration with Dr. John de Groot, we sequenced ~220 adult gliomas using a 200-gene panel. This study shows the pros and cons of current…

I took over this project from Roel in 2011. It has been more than 8 years! This mouse model-based study reveals a surprising opposite role…

This paper calls for the proteomics community to deploy standard file formats for storing and exchanging data.